Anyone else running into corruption with Excel 2010?

I had to right-click on the file in windows explorer and go to Properties for the file; On the first tab (“General”) at the bottom there was text that stated “This file came from another computer and might be blocked to help protect this computer”, next to the text was an “Unblock” button.  Selecting “Unblock” solved this issue.

This solved my problem with Excel reporting xls files as being corrupt.